Heterodimeric bispecific antibodies
US11634502B2 · kind B2 · utility
1Cited by
6References
24Claims
0Family size
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Key dates
| Filing date | Mar 13, 2014 |
| Grant date | Apr 25, 2023 |
| Priority date | — |
| Expiry date | Mar 13, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are heterodimeric bispecific antibodies that can mediate cytolysis of a target cell by an immune effector cell, nucleic acids encoding such antibodies, methods of making such antibodies, and methods of using such antibodies. These antibodies comprise two different polypeptide chains, each comprising two immunoglobulin variable regions and, optionally, a half life-extending moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.