Patent · US Active

Metabolic pathways with increased carbon yield

US11634701B2 · kind B2 · utility

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15Claims
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Assignee

Inventor

Key dates

Filing dateMar 1, 2019
Grant dateApr 25, 2023
Priority date—
Expiry dateApr 12, 2039

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02E50/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to the conversion of a carbon source into acetyl phosphate with increased carbon yield. In particular, the invention provides metabolically engineered micro-organisms capable of producing acetyl phosphate from a carbon source with increased carbon yield, which micro-organisms have been transformed with at least one exogenous nucleic acid encoding a phosphoketolase having sedoheptulose-7-phosphate phosphoketolase activity and which are further genetically modified to have eliminated transketolase activity. The invention also provides methods for the production of chemicals using said micro-organisms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.