Methods of treating based on site-specific tau phosphorylation
US11635440B2 · kind B2 · utility
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Key dates
| Filing date | Jun 17, 2022 |
| Grant date | Apr 25, 2023 |
| Priority date | — |
| Expiry date | Jun 17, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/14
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.