Method for preparing additive-free cell-wall-broken granule of Chinese medicinal material

US11638696B2 · kind B2 · utility

Assignee

• ZHONGSHAN ZHONGZHI PHARMACEUTICAL GROUP CO., LTD. · CN

Inventors

• Jinle Cheng · Longbeilingcun, CN
• Zhitian Lai · Longbeilingcun, CN
• Jiyin Xu · Longbeilingcun, CN
• Yongjun Chen · Rancho Cucamonga, US
• Wen Deng · Longbeilingcun, CN
• Lihua Peng · Longbeilingcun, CN
• Weixuan Chen · Cambridge, US
• Jinmei Chen · Longbeilingcun, CN
• Yina WANG · Tianjin, CN
• Yanling LIANG · Hunan, CN
• Weilin Qiao · Longbeilingcun, CN
• Xiaojun Cao · Longbeilingcun, CN

Key dates

• Filing date: Oct 21, 2020
• Grant date: May 2, 2023
• Expiry date: Jul 17, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2236/333
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a method for preparing an additive-free cell-wall-broken granule of a Chinese medicinal material. The cell-wall-broken granule is obtained by medicinal material concocting and grinding, first cell-wall-breaking and grinding, screening, second wall-breaking and grinding, mixing, pelleting, and granulating and sieving. The obtained granule has a moderate tightness, a relatively rapid dissolution and diffusion and a good uniformity, overcoming problems of a difficulty of dissolution and diffusion and a poor uniformity of the existing cell-wall-broken granules.