Transcutaneous neuromodulation system and methods of using same

US11638820B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Victor Reggie Edgerton · Los Angeles, US
• Yury Gerasimenko · Los Angeles, US
• Parag Gad · Calabasas, US
• Nicholas A. Terrafranca · Laguna Niguel, US

Key dates

• Filing date: Jan 4, 2021
• Grant date: May 2, 2023
• Expiry date: Mar 27, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/36171
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A neuromodulation system and a method of inducing voluntary movement in a mammal with a spinal injury are disclosed. In an example, a neuromodulation system includes a processor, a signal generator, and at least one electrode. The processor, in cooperation with the signal generator and the at least one electrode are configured to deliver a transcutaneous stimulation to a mammal. The transcutaneous stimulation includes during a first time period, a transcutaneous electrical spinal cord stimulation (“tESCS”) applied to the mammal during physical conditioning of the mammal. The transcutaneous stimulation also includes during a second time period after the first time period, the tESCS applied to the mammal during reduced or no physical conditioning of the mammal. The tESCS applied during the first time period and the second time period is used to establish a functional baseline of the mammal.