Oxazine compound and application thereof
US11639360B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 22, 2019 |
| Grant date | May 2, 2023 |
| Priority date | — |
| Expiry date | Apr 22, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6439
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.