Patent · US Active

Compounds for degrading Tau protein aggregates and uses thereof

US11642413B2 · kind B2 · utility

0Cited by

17References

30Claims

0Family size

Assignee

APRINOIA THERAPEUTICS LIMITED · CN

Inventors

Paul Tempest · Brookline, US
Ming-Kuei JANG · Taipei, TW
Yih-Shyan Lin · Kaohsiung, TW

Key dates

Filing date	Mar 4, 2022
Grant date	May 9, 2023
Priority date	—
Expiry date	Mar 4, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are novel compounds for degrading Tau protein aggregates, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof. Also disclosed herein are uses of the compounds, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof in manufacture a medicament for treating a tauopathy, as well as method for aiding in the treatment of a tauopathy or treating a tauopathy in a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.