Method of preparing polyvinyl alcohol nanofiber membrane enhancing cell specific adhesion
US11643634B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Feb 27, 2020 |
| Grant date | May 9, 2023 |
| Priority date | — |
| Expiry date | Jul 24, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2537/10
- WIPO fieldTextile and paper machines
- WIPO sectorMechanical engineering
Abstract
A method of preparing a polyvinyl alcohol nanofiber membrane includes a material for controlling cell specific adhesion, and a nanofiber membrane that can maintain cellular functions such as cell activity and growth is prepared by adding aqueous solutions containing a polyacrylic acid and a glutaraldehyde crosslinking agent in a polyvinyl alcohol and materials capable of enhancing or regulating cell adhesion, electrospinning, treating with hydrochloric acid vapor and dimethylformaldehyde solvent and treating with sodium hydroxide to control the cell adhesion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.