Establishment and application of human immortalized B lymphocyte cell line group
US11643637B2 · kind B2 · utility
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Key dates
| Filing date | Nov 9, 2018 |
| Grant date | May 9, 2023 |
| Priority date | — |
| Expiry date | Jan 18, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/91
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present application provides a group of human immortalized B lymphocyte cell lines and use thereof, and specifically provides a combination of four closely related immortalized lymphocyte cell lines. The combination can be used as a reference substances for measuring the performance of a detection platform. When the four closely related immortalized lymphocyte cell lines are used as reference substances for epigenome, transcriptome, proteome, and metabolome, an intrinsic magnitude difference gradient can be formed to evaluate the sensitivity of histological detection.
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