Method for detecting C. perfringens induced diseases in animals

US11643696B2 · kind B2 · utility

Assignee

• Evonik Operations GmbH · DE

Inventors

• Monika FLÜGEL · Steinhagen, DE
• Stefan Pelzer · Gütersloh, DE
• Filip Van Immerseel · Eke, BE
• Richard Ducatelle · Oudenaarde, BE
• Evy Goossens · Wachtebeke, BE
• Sarah HARK · Gütersloh, DE
• Frank THIEMANN · Nottuln, DE
• Florian BÖHL · Neckargemünd, DE

Key dates

• Filing date: May 9, 2018
• Grant date: May 9, 2023
• Expiry date: Nov 19, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for detecting C. perfringens induced diseases in animals, the method comprising: a) collecting sample material of a specific animal or of a specific group of animals at consecutive points in time; b) determining the amount of a first marker and a second marker contained in the sample material; and c) determining the ratio of the first marker to the second marker contained in the sample material; wherein the first marker comprises a polynucleotide sequence being specific for the C. perfringens sub-species inducing the targeted disease; and the second marker comprises a polynucleotide being specific for the species C. perfringens; and wherein an increase in the ratio of the first marker to the second marker in the analyzed sample material over time is an indication of the targeted disease.