Systems and methods for electrode orientation determination in deep brain stimulation (DBS)

US11648063B2 · kind B2 · utility

Assignee

• Advanced Neuromodulation Systems, Inc. · US

Inventors

• Yagna Pathak · Skokie, US
• Hyun-Joo Park · Cleveland, US
• Simeng Zhang · Frisco, US
• Anahita Kyani · Plano, US
• Erika Ross · Dallas, US
• Dehan Zhu · Plano, US
• Douglas Alfred Lautner · Round Lake, US

Key dates

• Filing date: Dec 7, 2020
• Grant date: May 16, 2023
• Expiry date: Jul 16, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G06V2201/031
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present disclosure provides systems and methods for estimating an orientation of an implanted deep brain stimulation (DBS) lead. Such methods include generating an initial image dataset, down-sampling a respective image or adding noise to images of the subset of the initial image dataset, and re-slicing at least a subset of the modified image dataset along an alternative primary imaging axis, to generate an integrated image dataset. The method also include partitioning the integrated image dataset into a preliminary training image dataset and a testing image dataset, and re-sizing at least a subset of the preliminary training image dataset with a localized field of view around a depicted DBS lead, to generate a training image dataset. The method further includes training a machine-learning model using the training image dataset, and executing the trained machine-learning model to estimate, during a DBS implantation procedure, an orientation of a subject implanted DBS lead.