Patent · US Active

Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors

US11648243B2 · kind B2 · utility

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85References
20Claims
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Assignee

Inventors

Key dates

Filing dateDec 1, 2020
Grant dateMay 16, 2023
Priority date
Expiry dateJul 8, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are compounds of the Formula I: or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.