Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling
US11648254B2 · kind B2 · utility
2Cited by
1References
30Claims
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Key dates
| Filing date | Mar 2, 2022 |
| Grant date | May 16, 2023 |
| Priority date | — |
| Expiry date | Mar 2, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides compounds represented by Formula (I-1): and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.