Patent · US Active

Crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and new salts

US11654144B2 · kind B2 · utility

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Key dates

Filing dateJan 25, 2021
Grant dateMay 23, 2023
Priority date
Expiry dateAug 11, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/565
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1-yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water (“hydrates”). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.

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