Patent · US Active

Compositions and methods for enhancing the stability of transgenes in poxviruses

US11654189B2 · kind B2 · utility

0Cited by

0References

21Claims

0Family size

Assignee

Bavarian Nordic A/S · DK

Inventors

Markus Kalla · Penzberg, DE
Ryan Rountree · San Mateo, US
Ulrike Dirmeier · Starnberg, DE

Key dates

Filing date	Jul 5, 2021
Grant date	May 23, 2023
Priority date	—
Expiry date	Nov 18, 2041

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are recombinant poxviruses that are stable through successive passaging of the recombinant poxviruses. More particularly, the recombinant poxviruses comprise one or more modified nucleic acids encoding MUC1, CEA, and/or TRICOM antigens, wherein the recombinant poxviruses are stable through successive passaging. Also, provided herein are compositions and method related thereto.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.