Patent · US Active

Crystal form of compound and fumaric acid, pharmaceutical composition and method for treating coronavirus-induced diseases

US11655240B1 · kind B1 · utility

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20Claims
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Key dates

Filing dateOct 12, 2022
Grant dateMay 23, 2023
Priority date
Expiry dateOct 12, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure provides a crystal form of a compound and fumaric acid, an active pharmaceutical ingredient and a pharmaceutical composition containing the same, and a method for treating coronavirus-induced diseases a using the same. In particular, the crystal form of the present disclosure comprises the compound of Formula (I) and fumaric acid, and the X-ray powder diffraction pattern of the crystal form obtained using Cu-Kα radiation includes at least three peaks selected from the group consisting of: 0.94°±0.2° 2θ, 19.06°±0.2° 2θ, 23.50°±0.2° 2θ, and 24.66°±0.2° 2θ. The crystal form of the present disclosure has a high purity, good stability, and a high melting point.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.