Engineered cells with decreased gene expression resulting in increased viral production
US11655471B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Mar 8, 2018 |
| Grant date | May 23, 2023 |
| Priority date | — |
| Expiry date | Mar 8, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions and methods for increasing virus production. In particular, disclosed herein are cell or cell line comprises reduced expression of one or more cellular genes selected from the group comprising COQ9, FGF2, NAT9, NDUFA9, NEU2, PLA2G1B, PYCR1, RAD51AP1, STRADA, SVOPL, and/or ZFYVE9 for use in increasing viral production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.