High intensity labeled reactant compositions and methods for sequencing
US11655504B2 · kind B2 · utility
1Cited by
74References
18Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 24, 2018 |
| Grant date | May 23, 2023 |
| Priority date | — |
| Expiry date | Jul 26, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compositions useful for the detection of single molecules in a sample are provided. In some aspects, the disclosure provides a nucleic acid connected to a nucleotide and two or more luminescent labels. In some embodiments, the nucleic acids described herein comprise one or more structural features that provide enhanced fluorescence intensity. In some aspects, methods of sequencing using the labeled nucleotides of the disclosure are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.