Media, methods, and systems for protein design and optimization
US11657894B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Jul 6, 2021 |
| Grant date | May 23, 2023 |
| Priority date | — |
| Expiry date | Jul 6, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/20
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Exemplary embodiments relate to a protein engineering pipeline configured to optimize or improve proteins for specified functions. The problem space of such a task can grow quickly based on the sequence of the protein being optimized and the functions for which the protein is being designed. The solutions described herein allow the problem space to be efficiently searched by applying a combination of a protein design pipeline and an evaluation procedure performed on a quantum computer. As a result, single or multiple amino acid substitutions at a site of interest may be predicted in order to generate optimized protein variants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.