Particles comprising a shell with RNA

US11660338B2 · kind B2 · utility

Assignees

• BIONTECH SE · DE
• TRON · DE

Inventors

• Ugur Sahin · Mainz, DE
• Heinrich Haas · Mainz, DE
• Sebastian Kreiter · Mainz, DE
• Yves Hüsemann · Wiesbaden, DE
• Mustafa Diken · Mainz, DE
• Kerstin Reuter · Darmstadt, DE
• Hossam Hefesha · Wiesbaden, DE

Key dates

• Filing date: Jan 22, 2020
• Grant date: May 30, 2023
• Expiry date: Nov 23, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2810/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to RNA decorated particles such as RNA decorated lipid particles, preferably to RNA decorated liposomes. Further, the present invention relates to a pharmaceutical composition comprising RNA decorated particles such as RNA decorated lipid particles, preferably RNA decorated liposomes. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the RNA decorated particles such as RNA decorated lipid particles, preferably RNA decorated liposomes.