Device, system, and formulation for oral delivery of functionalized particles
US11660436B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2020 |
| Grant date | May 30, 2023 |
| Priority date | — |
| Expiry date | Aug 16, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/04
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A device includes a capsule sized to pass through a lumen of a gastrointestinal tract; an enteric coating surround at least a portion of the capsule and configured to protect the capsule form stomach acid while allowing degradation of the capsule in the small intestine of the gastrointestinal tract; a plurality of functionalized particles disposed within the capsule, a plurality of tissue penetrating members configured to puncture a wall of the lumen of the intestinal tract; and an actuator having a first configuration and a second configuration. The actuator is configured to retain the plurality of functionalized particles within the capsule in the first configuration. The actuator is further configured to advance the plurality of functionalized particles from the capsule into a wall of the lumen of the gastrointestinal tract via the plurality of tissue penetrating members by the actuator transitioning from the first configuration to the second configuration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.