Compound containing fused ring, use thereof and pharmaceutical composition containing same

US11661420B2 · kind B2 · utility

Assignee

• NANJING HEPO PHARMACEUTICAL CO., LTD · CN

Inventors

• Pengfei QIAN · Shanghai, CN
• Fengbo Li · 安丰镇, CN
• Xuejun Liu · Shanghai, CN
• Xiaodong Chen · Lo Wu, CN
• Lijun Guo · 安丰镇, CN
• Kai Sun · Shanxi, CN

Key dates

• Filing date: Apr 22, 2020
• Grant date: May 30, 2023
• Expiry date: Apr 22, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are a compound containing a fused ring, a use thereof and a pharmaceutical composition containing same. Provided are a compound as shown in formula I-A, a pharmaceutically acceptable salt thereof, a solvate thereof, a solvate of the pharmaceutically acceptable salt thereof or a crystal form thereof. The compound can significantly reduce the levels of HBsAg, HBeAg and HBV DNA, and can be used for preparing a drug for treating hepatitis B, and has good market prospects. (I-A)