Tetrazole derivatives as TRPA1 inhibitors

US11661430B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Florian Paul Christian Binder · Maselheim, DE
• Thomas Martin FLECK · Munich, DE
• Jens WILLWACHER · Biberach an der Riß, DE

Key dates

• Filing date: Oct 13, 2021
• Grant date: May 30, 2023
• Expiry date: Oct 13, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P11/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing the same.