Anti-NRP1A antibodies and their uses for treating eye or ocular diseases

US11661458B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Nina ZIPPEL · Biberach an der Riß, DE
• Pankaj Gupta · Scarsdale, US
• Fei HAN · Sandy Hook, US
• Sarah Low · Carmel, US
• Juergen PRESTLE · Biberach an der Riß, DE
• Leo Thomas · Biberach, DE

Key dates

• Filing date: Sep 24, 2020
• Grant date: May 30, 2023
• Expiry date: Sep 24, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are antibodies and fragments thereof that target the A-domain of Neuropilin-1 (Nrp1A). Also disclosed are methods of using the anti-Nrp1A antibodies for the treatment of various diseases or disorders.