Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
US11661459B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Dec 1, 2021 |
| Grant date | May 30, 2023 |
| Priority date | — |
| Expiry date | Dec 1, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are polynucleotides encoding inactivated cell surface receptors. Also provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.