Method of inhibiting tau phosphorylation
US11661580B2 · kind B2 · utility
0Cited by
19References
11Claims
0Family size
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Key dates
| Filing date | Aug 28, 2020 |
| Grant date | May 30, 2023 |
| Priority date | — |
| Expiry date | Dec 29, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of inhibiting phosphorylation of the tau protein and/or a TLR4-mediated immune response is disclosed. The method contemplates administering to cells in recognized need thereof such as cells of the central nervous system an effective amount of a of a compound or a pharmaceutically acceptable salt thereof that binds to a pentapeptide of filamin A (FLNA) of SEQ ID NO: 1, and contains at least four of the six pharmacophores of FIGS. 35-40.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.