Light-emitting molecules
US11661587B2 · kind B2 · utility
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15Claims
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Assignee
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Key dates
| Filing date | Aug 12, 2019 |
| Grant date | May 30, 2023 |
| Priority date | — |
| Expiry date | Aug 12, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y113/12
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are luciferase polypeptides with improved light-emitting activity and their encoding nucleic acids. These molecules are useful in a range of assays including luciferase-based gene reporter assays, bioluminescence resonance energy transfer assays, protein complementation assays and other applications in which luciferase enzymes are utilized as detectable and/or quantifiable labels. Also disclosed are methods and compositions for increasing the sensitivity and/or improving the kinetics of luciferase-catalyzed reactions as well as decreasing the impact of undesirable variables.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.