Method for spectral study of a biological fluid

US11662303B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• Université Paris—Est Créteil Val de Marne · FR
• ETABLISSEMENT FRANCAIS DU SANG (EFS) · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR

Inventors

• Laurent KIGER · Paris, FR
• Michael Marden · Aulnay-sous-Bois, FR
• Pablo BARTOLUCCI · L'Haÿ-les-Roses, FR
• France PIRENNE · Paris, FR

Key dates

• Filing date: Nov 30, 2018
• Grant date: May 30, 2023
• Expiry date: Dec 29, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/48
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The aim of the present invention is to propose a novel method for spectral study of a biological fluid from an absorption spectrum of a sample of the biological fluid. The inventors have made an original use of spectroscopy in order to accurately determine the protein content of a biological sample, in particular for oxyhaemoglobin, methaemoglobin, bilirubin and the haem bound to serum albumin. Such a method can be used in a variety of applications concerning haem- or haemoprotein- related diseases, in particular diagnostic methods, treatment follow-up methods, methods for determining biomarkers or screening methods. Such a method is also advantageous for qualifying blood bags.