Drug implants containing enzalutamide and methods of use thereof

US11666528B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• Alessa Therapeutics, Inc. · US

Inventors

• Maithili Rairkar · San Francisco, US
• Pujan Desai · Oakland, US
• Carlos Schuler · Cupertino, US
• Keith Hall · San Francisco, US
• Pamela Munster · Hillsborough, US
• John Maroney · San Francisco, US
• Scott Thomas · Oakland, US

Key dates

• Filing date: Apr 25, 2022
• Grant date: Jun 6, 2023
• Expiry date: Apr 25, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are drug implants comprising enzalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and enzalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.