Patent · US Active

Two-dimensional (2D) bismuth nanocomposite, and preparation method and use thereof

US11667541B2 · kind B2 · utility

0Cited by

0References

14Claims

0Family size

Assignee

Henan University · CN

Inventors

Bingyang Shi · Kaifeng, CN
Jiefei Wang · Kaifeng, CN
Ping Shangguan · Kaifeng, CN
Yong Zhong · Lo Wu, CN
Zhongjie Wang · Beijing, CN
Xiaoyu Chen · Nanhu, CN

Key dates

Filing date	Dec 21, 2020
Grant date	Jun 6, 2023
Priority date	—
Expiry date	Aug 13, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC01P2004/64
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure relates to a two-dimensional (2D) bismuth nanocomposite, and a preparation method and use thereof, and belongs to the field of nanobiotechnology. The 2D bismuth nanocomposite of the disclosure is an ultra-thin bismuth nanosheet that is loaded with platinum nanoparticles and modified with indocyanine green (ICG) and surface targeting polypeptide Ang-2. The 2D bismuth nanocomposite Bi@Pt/ICG-Ang2 of the disclosure can not only realize the targeted photothermal and photodynamic combination therapy for tumors, but also realize the dual-mode imaging combining CT and fluorescence imaging.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.