FGFR4 inhibitor, preparation method therefor, and applications thereof
US11667631B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 16, 2017 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | May 16, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an FGFR4 inhibitor having a structure represented by formula (I), preparation method therefor, and applications thereof. A series of compounds represented by formula (I) in the present invention have very-strong inhibition effect on the activity of FGFR4 kinase, have very-high selectivity, can be widely used in the preparation of drugs for treating cancers, specially a liver cancer, a stomach cancer, a prostate cancer, a skin cancer, an ovarian cancer, a lung cancer, a breast cancer or a colon cancer, and can be developed into a new-generation FGFR4 inhibitor drug.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.