Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements
US11667648B2 · kind B2 · utility
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Key dates
| Filing date | Mar 9, 2020 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | Feb 17, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided herein are cell-permeable, cell-compatible, and chemoselectively-cleavable linkers for tethering (e.g., covalently) functional elements (e.g., a cellular interaction element and a capture element), and methods of use (e.g., intracellular capture and extracellular release of cellular targets) therewith.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.