Antibodies binding to human IL-4R, preparation method therefor and use thereof
US11667717B2 · kind B2 · utility
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Key dates
| Filing date | Aug 20, 2019 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | Nov 13, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are antibodies binding to human IL-4R, having identical variable regions and different constant regions, wherein the variable regions can specifically bind to human IL-4R, and the constant regions affect the activity of the whole antibody through an amino acid site mutation. The above-mentioned antibodies can be used to treat diseases related to IL-4R overexpression, such as atopic dermatitis, asthma, etc., and thus possesses good clinical application prospects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.