Method of selectively differentiating undifferentiated macrophage into M1 macrophage
US11667891B2 · kind B2 · utility
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Key dates
| Filing date | Jun 10, 2020 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | May 30, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/74
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided is a method for the selective differentiation into M1 macrophages under a pressurized environment, and more particularly, a method for the selective differentiation of undifferentiated macrophages into M1 macrophages, the method including incubating the undifferentiated macrophages in an incubator under the pressurized environment. In addition, provided is a method for producing osteoclasts, the method including: incubating undifferentiated macrophages in an incubator under a pressurized environment to differentiate into M1 macrophages; and differentiating the differentiated M1 macrophages into osteoclasts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.