Multiplexed diagnostic assay for iron and vitamin A deficiency and methods of use thereof
US11668711B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 2018 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | Jan 3, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2470/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A diagnostic assay strip includes a first layer that includes an iron mobile labelled specific binding partner that will bind to and iron biomarker from a sample and produce an iron complex and a vitamin A mobile labelled specific binding partner that will bind to a vitamin A biomarker from the sample and produce a vitamin A complex. A second layer includes iron and vitamin A test regions, and a control region. The iron test region has immobilized specific binding partners that will bind to the iron complex. The vitamin A test region has immobilized vitamin A biomarker that will bind to vitamin A mobile labelled specific binding partner, which is not bound to the vitamin A biomarker, passing from the first layer to the second layer. The control region has a moiety which will non-specifically bind to and immobilize the iron and vitamin A labelled specific binding partners. Methods of using the diagnostic assay strip are also discussed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.