Artificial valved conduits for cardiac reconstructive procedures and methods for their production
US11672651B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 7, 2020 |
| Grant date | Jun 13, 2023 |
| Priority date | — |
| Expiry date | Aug 28, 2040 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T29/49412
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.