Radiation mitigator and method of use thereof

US11672789B2 · kind B2 · utility

Assignees

• Georgetown University · US
• The Board of Regents of the University of Oklahoma · US

Inventors

• Milton L. Brown · Brookeville, US
• Yali Kong · Fairfax, US
• Courtney Houchen · Edmond, US
• Sripathi M. Sureban · Oklahoma City, US
• Parthasarathy Chandrakesan · Edmond, US

Key dates

• Filing date: Apr 25, 2022
• Grant date: Jun 13, 2023
• Expiry date: Apr 25, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are methods useful for preventing and mitigating radiation injury, including acute radiation syndrome, comprising administering to a subject a therapeutically effective amount of a compound represented by formula I or a pharmaceutically acceptable salt thereof, wherein Z is —O— or —N(H)—.