Development of amnion-like tissue from human pluripotent stem cells

US11672832B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• Jianping Fu · Cambridge, US
• Deborah Gumucio · Ann Arbor, US
• Yue Shao · Moraine, US
• Kenichiro Taniguchi · Ann Arbor, US
• Yi Zheng · Wilmington, US
• Sajedeh Nasr Esfahani · Ann Arbor, US

Key dates

• Filing date: Dec 8, 2017
• Grant date: Jun 13, 2023
• Expiry date: Sep 28, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides compositions and methods employing stem cell-derived amnion tissue. In some embodiments, compositions (e.g., scaffolds and devices) and methods of generating amnion-like tissues from hPSCs are provided. In some embodiments, uses of such cells for research, compound screening and analysis, and therapeutics are provided.