Protein-templated self-assembly of a covalent polymer network for intracellular trafficking and traceless release
US11672867B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Mar 30, 2018 |
| Grant date | Jun 13, 2023 |
| Priority date | — |
| Expiry date | Feb 12, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides polymers and polymer-based nano-structures, in particular, polymers and polymer network to which biomolecules (e.g., proteins, antibodies, peptide aptamers) can be covalently conjugated and stably encapsulated therein and be controllably delivered and released upon degradation of the nano-structures in response to specific microenvironment, and compositions and methods of preparation and use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.