Anti-transferrin receptor antibody and uses thereof

US11672872B2 · kind B2 · utility

Assignee

• Dyne Therapeutics, Inc. · US

Inventors

• Romesh R. Subramanian · Framingham, US
• Mohammed T. Qatanani · Waltham, US
• Timothy Weeden · Waltham, US
• Cody A. Desjardins · Waltham, US
• Brendan Quinn · Boston, US
• John Najim · Waltham, US

Key dates

• Filing date: Jul 8, 2022
• Grant date: Jun 13, 2023
• Expiry date: Jul 8, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Aspects of the disclosure relate to antibodies that bind to transferrin receptor (e.g., transferrin receptor 1) and complexes comprising the antibody covalently linked to a molecular payload. Methods of using the antibodies are also provided.