Compositions and methods for diagnosis and treatment of cancer

US11673939B2 · kind B2 · utility

Assignee

• BIONTECH SE · DE

Inventors

• Ugur Sahin · Mainz, DE
• Bonny Gaby Lui · Mainz, DE
• Nadja Salomon · Hochheim, DE
• Joycelyn Wüstehube-Lausch · Worms, DE
• Matin Daneschdar · Budenheim, DE
• Hans-Ulrich Schmoldt · Darmstadt, DE
• Markus Fiedler · Bodenwerder, DE

Key dates

• Filing date: Jun 6, 2019
• Grant date: Jun 13, 2023
• Expiry date: Jun 6, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to the diagnosis and treatment of diseases expressing Fibronectin Extra Domain B (EDB) such as diseases characterized by tissue remodeling and/or angiogenesis, in particular cancerous diseases, such as head and neck, brain, colorectal, lung, prostate and breast cancer. More particularly, the invention concerns peptides targeting Fibronectin Extra Domain B.