DNA-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
US11674135B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Jul 12, 2013 |
| Grant date | Jun 13, 2023 |
| Priority date | — |
| Expiry date | Aug 29, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to complexes of oligonucleotide-encoded libraries and methods of tagging and using such libraries. In particular, the oligonucleotides and methods can include complexes having at least one linkage for which a polymerase has reduced ability to read or translocate through.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.