Universal antibody libraries
US11674240B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jul 6, 2005 |
| Grant date | Jun 13, 2023 |
| Priority date | — |
| Expiry date | Dec 14, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Universal antibody libraries are described which are synthetic and derived from expressed human antibody sequences selected accordingly to certain criteria, for example, that the sequences are derived from naturally-occurring antibodies expressed in response to a certain antigen class (e.g., small molecule, polysaccharide, peptide, or protein) and having CDR regions engineered for optimal diversity. Methods for making and screening such libraries for isolating therapeutics suitable for treating disease are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.