Methods determining and treating cellular resistance to ADP-rtbosylating toxin
US11674950B2 · kind B2 · utility
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35Claims
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Key dates
| Filing date | Oct 30, 2018 |
| Grant date | Jun 13, 2023 |
| Priority date | — |
| Expiry date | Oct 19, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is based in part on the identification of DPH1 and other members of the diphthamide synthesis pathway as biomarkers of resistance to an ADP-ribosylating toxin in a cell, and methods for identification, assessment, and treatment of a condition that is resistant to an ADP-ribosylating toxin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.