Methods of treating disorders using CSF1R inhibitors

US11679110B2 · kind B2 · utility

Assignee

• Deciphera Pharmaceuticals, LLC · US

Inventors

• Daniel L. Flynn · Lawrence, US
• Bryan D. Smith · Madison, US
• Rodrigo Ruiz Soto · Waltham, US
• Keisuke Kuida · Waltham, US

Key dates

• Filing date: Jun 25, 2021
• Grant date: Jun 20, 2023
• Expiry date: Sep 19, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are methods of treating cancers and other tumors related to the decreased proliferation, the depletion, or the repolarization of tumor-associated macrophages (TAMs) and treatment of associated disorders, including tenosynovial giant cell tumor (TGCT) and diffuse-type tenosynovial giant cell tumor (DTGCT).