Patent · US Active

Live-attenuated flaviruses with heterologous antigens

US11680084B2 · kind B2 · utility

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0References

22Claims

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Assignee

Katholieke Universiteit Leuven · BE

Inventors

Robbert Boudewijns · Essen, BE
Kai Dallmeier · Kessel-Lo, BE
Johan Neyts · Namur, BE

Key dates

Filing date	Oct 5, 2018
Grant date	Jun 20, 2023
Priority date	—
Expiry date	Dec 17, 2038

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to polynucleotides comprising the sequence of a flavivirus preceded by a sequence encoding an N terminal part of a flavivirus Capsid protein, an immunogenic protein, or a part thereof comprising a an immunogenic peptide, and a 2A cleaving peptide, and to the virus encoded by such sequences. The invention further relates to the use of such polynucleotides and viruses as vaccines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.