Patent · US Active

Method and system for separating biomolecules

US11686726B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

CYTIVA SWEDEN AB · SE

Inventors

Ola Lind · Uppsala, SE
Johan Avallin · Uppsala, SE
Andreas Torbjorn Lundin · Uppsala, SE
Nils Norrman · Uppsala, SE
Ronnie Palmgren · Uppsala, SE
Gustav Rodrigo · Uppsala, SE

Key dates

Filing date	Dec 27, 2017
Grant date	Jun 27, 2023
Priority date	—
Expiry date	Sep 26, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/31
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A separation system, a method in a separation system and an elution arrangement to be provided in a separation system for separating a biomolecule from a cell culture are provided. The method comprises the steps of: —providing a feed from a cell culture (3; 103; 203) comprising said biomolecule to a magnetic separator (5; 105; 205) and providing to the magnetic separator magnetic beads comprising ligands capable of binding this biomolecule; —separating by the magnetic separator said magnetic beads with bound biomolecules from the rest of the feed; —forwarding said magnetic beads as a slurry with an added buffer to an elution cell (7; 107; 207); —eluting the bound biomolecules in the elution cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.