Process for preparing 2,6-dialkylphenylacetic acids
US11691938B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Apr 3, 2019 |
| Grant date | Jul 4, 2023 |
| Priority date | — |
| Expiry date | Apr 3, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F3/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5) activation of the benzyl alcohol obtained, (6) cyanation of the activated benzyl alcohol and (7) hydrolysis of the nitrile obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.