Heterocyclic compounds, preparation methods therefor, and methods of uses thereof

US11691981B2 · kind B2 · utility

Assignee

• INVENTISBIO CO., LTD. · CN

Inventors

• Xing Dai · Cranford, US
• Yaolin Wang · Short Hills, US
• Yueheng Jiang · Shanghai, CN
• Yanqin LIU · Shanghai, CN
• Haotao NIU · Shanghai, CN
• Zhenwu Wang · Shanghai, CN
• Zixing HAN · Shanghai, CN
• Liangshan TAO · Shanghai, CN
• Jifang WENG · Shanghai, CN
• Zhe SHI · Shanghai, CN

Key dates

• Filing date: Jun 24, 2020
• Grant date: Jul 4, 2023
• Expiry date: Jun 24, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are novel heterocyclic compounds, for example, compounds having Formula I. Also provided herein are methods of preparing the compounds and methods of using the same, for example, in inhibiting TGF-beta mediated signaling and/or for treating cancer.