Implantable drug eluting device comprising a microporous structure

US11696830B2 · kind B2 · utility

Assignee

• WALDEMAR LINK GmbH & Co. KG · DE

Inventors

• Eckhard Bauer · Kiel, DE
• Helmut D. Link · Hamburg, DE

Key dates

• Filing date: Oct 11, 2018
• Grant date: Jul 11, 2023
• Expiry date: Oct 11, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2300/416
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Implantable drug-eluting device (1) comprising a microporous structure (2) having regularly arranged pores (4, 5) in at least two different uniform sizes, and manufacturing method. The pores are configured for receiving a drug (9) and are being connected by interconnections (6, 7). Interconnections (6) originating from pores (4) of a first size have a first elution area and interconnections (7) originating from pores (5) of a second size have a second elution area. The interconnections convey the drug (9) to a surface of the device for elution to surrounding tissue. The ratio between the first and the second elution areas is predefined and selectable. The differently sized elution areas provide for different outflow rates. This allows for simple but reliable dispensing of drugs at positively controlled and well determined rates. Particularly, this enables a single implantable device to dispense drugs over preselectable durations of time, like short-term or long-term.